Modelling ART impact on HIV prevention within discordant couples
The HPTN 052 study, discussed in an earlier blog, appears to offer a godsend: a demonstrated 96% reduction in HIV transmission in discordant couples using antiretroviral therapy (ART). Apparently,...
View ArticleWhat can cost-effectiveness modelling tell us about the feasibility of...
The WHO global initiative for the elimination of congenital syphilis (2007) set the goal of expanding antenatal testing to >90% by 2015. In sub-Saharan Africa (SSA) recent estimates place the...
View ArticleAre African HIV epidemics sustained by exogenous introduction of infection?
What is the relative importance of exogenous and endogenous transmission in sustaining HIV epidemics? In a study of HIV sub-type distribution in the Middle East, Mumtaz & Abu Raddad (STIs) stress...
View ArticleAchieving HPV herd immunity cost-effectively. When does it make sense to...
Recent empirical studies of HPV vaccination have provided evidence that marginal vaccination costs increase with coverage. Let us take into account – they argue – not just the vaccine price, but the...
View ArticleIncreased HIV infectivity in the acute phase of infection may be a less...
Assessing, as far as we can, the preventative impact of ART on HIV transmission dynamics is evidently very important – both to inform judgments about ART initiation (Wayal & Hart (STI); Cohen...
View ArticleModeling the potential effectiveness of PrEP as against other preventative...
Despite the known preventative benefits of ART, the incidence of HIV among UK MSM population has remained relatively constant over the last 10 years and looks set to remain so. The UN 90:90:90 target...
View ArticleMathematical models say: switching to HPV nonavalent vaccine brings cost...
STI journal issues of nearly a decade ago, when HPV vaccination was a relatively new thing, hosted a discussion on the issue of which vaccine to choose. The choice at that time, readers will remember,...
View ArticleIs increasing gonorrhoea resistance in MSM is a result of more treatment,...
Emerging antibiotic resistance to the last-ditch treatment of Neisseria gonorrhoeae compels health policy-makers to balance opposing concerns. On the one hand, successfully combating spread of the...
View ArticleEstimating the added value of PrEP where it is not the only prevention tool...
LeVasseur & Welles (L&W) model the potential population-level impact of PrEP in combination with other prevention strategies. They seek to quantify the additional benefit of PrEP at various...
View ArticleCan we use online search query data to predict the next syphilis outbreak?
Considerable stir has been generated by Young & Aral (Y&A) in a recent modelling study claiming to have demonstrated the potential of Google online search data to identify and predict syphilis...
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